Polyelectrolyte Multilayer Films Based on Natural Polymers: From Fundamentals to Bio-Applications

Natural polymers are of great interest in the biomedical field due to their intrinsic properties such as biodegradability, biocompatibility, and non-toxicity. Layer-by-layer (LbL) assembly natural is a versatile, simple, efficient, reproducible, flexible bottom-up technique for development nanostructured materials controlled manner. The multiple morphological structural advantages LbL compared traditional coating methods (i.e., precise control over thickness compositions at nanoscale, simplicity, versatility, suitability, flexibility coat surfaces with irregular shapes sizes), make one most useful techniques building up advanced multilayer polymer structures application several fields, e.g., biomedicine, energy, optics. This review article collects main advances concerning employing used dipping, spray, spin coating) leading influence variables pH, molar mass, method preparation) this process. Finally, employment these biopolymer films platforms tissue engineering, drug delivery, thermal therapies will be discussed.