Polymorphisms in melatonin synthesis pathways: possible influences on depression
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چکیده
منابع مشابه
Polymorphisms in melatonin synthesis pathways: possible influences on depression
BACKGROUND It has been reported that rs4446909, a single nucleotide polymorphism (SNP) in the promoter of acetylserotonin methyltransferase (ASMT), influences the expression of the ASMT enzyme. The common G allele is associated with lower ASMT activity, and therefore, diminishes conversion of N-acetylserotonin to melatonin. The G allele was associated with recurrent depressive disorder in a Pol...
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ژورنال
عنوان ژورنال: Journal of Circadian Rhythms
سال: 2011
ISSN: 1740-3391
DOI: 10.1186/1740-3391-9-8