Polyspecific antigen binding by bovine immunoglobulin heavy- and light-chain variable domains
نویسندگان
چکیده
منابع مشابه
The association of heavy and light chain variable domains in antibodies: implications for antigen specificity
The antigen-binding site of immunoglobulins is formed by six regions, three from the light and three from the heavy chain variable domains, which, on association of the two chains, form the conventional antigen-binding site of the antibody. The mode of interaction between the heavy and light chain variable domains affects the relative position of the antigen-binding loops and therefore has an e...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2013
ISSN: 1664-3224
DOI: 10.3389/conf.fimmu.2013.02.01177