Positive Effect of Electroacupuncture Treatment on Gut Motility in Constipated Mice Is Related to Rebalancing the Gut Microbiota

نویسندگان

چکیده

Functional constipation (FC) is a common and often recurrent functional bowel disorder that seriously affects the quality of life affected individuals incurs significant economic burden on both individual society. There accumulating evidence intestinal dysbiosis contributes to rebalancing gut microbiota may be novel therapeutic modality for FC. Electroacupuncture (EA) has been shown restore normal levels in variety diseases. Additionally, several high-quality clinical studies have confirmed EA an effective, sustained, safe treatment However, whether effects are secondary changes how modulates induced by unknown. Therefore, here, we focused potential regulatory mechanisms diphenoxylate-induced mice analyzing structural microbiota. Our results showed effectively rebalanced constipated mice, mainly decreasing Firmicutes/Bacteroidetes ratio, which represent one way promotes gastrointestinal motility alleviates constipation. findings lay foundation further mechanistic research into application patients with

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ژورنال

عنوان ژورنال: Evidence-based Complementary and Alternative Medicine

سال: 2021

ISSN: ['1741-427X', '1741-4288']

DOI: https://doi.org/10.1155/2021/6652017