Potentiometric Determination of Trace Amounts of Amantadine Using a Modified Carbon-Paste Electrode

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Potentiometric determination of trace amounts of amantadine using a modified carbon-paste electrode.

A chemically modified carbon-paste electrode has been described for the sensitive and selective determination of amantadine. Beta-cyclodextrin was used as modifier. The electrode shows a sub-Nernstian response of 51.0 +/- 1.0 mV decade(-1) for amantadine in the concentration range of 6.3 x 10(-10)-7.1 x 10(-7) M at 25 degrees C. The optimum pH value was maintained at 4.5 using a 0.02 M acetate ...

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ژورنال

عنوان ژورنال: Analytical Sciences

سال: 2009

ISSN: 0910-6340,1348-2246

DOI: 10.2116/analsci.25.1227