p,p′-DDE Induces Apoptosis of Rat Sertoli Cells via a FasL-Dependent Pathway
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p,p′-DDE Induces Apoptosis of Rat Sertoli Cells via a FasL-Dependent Pathway
One,1-dichloro-2,2 bis(p-chlorophenyl) ethylene (p,p'-DDE), the major metabolite of 2,2-bis(4-Chlorophenyl)-1,1,1-trichloroethane (DDT), is a known persistent organic pollutant and male reproductive toxicant. It has antiandrogenic effect. However, the mechanism by which p,p'-DDE exposure causes male reproductive toxicity remains unknown. In the present study, rat Sertoli cells were used to inve...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2009
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2009/181282