Practical Use of Immortalized Cells in Medicine: Current Advances and Future Perspectives

Stem cells for clinical use in cardiovascular medicine: current limitations and future perspectives.

Cell transplantation is currently gaining a growing interest as a potential new means of improving the prognosis of patients with cardiac failure. The basic assumption is that left ventricular dysfunction is largely due to the loss of a critical number of cardiomyocytes and that it can be partly reversed by implantation of new contractile cells into the postinfarction scars. Primarily for pract...

Modeling Tumorigenesis in Drosophila: Current Advances and Future Perspectives

The Recent Advances and Future Perspectives of Personalized Medicine

Youming Zhang1* and Xiaodan Yao2 1Section of Genomic Medicine, Division of Respiratory Sciences, Imperial College London, UK 2National Clinical Research Centre of Kidney Diseases, Jinling Hospital School of Medicine, Nanjing University, China *Corresponding author: Dr. Youming Zhang, Molecular Genetics and Genomics Group, National Heart and Lung Institute, Dovehouse Street, London SW3 6LY, UK, ...

Down Syndrome: Current Status, Challenges and Future Perspectives

Down syndrome (DS) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. It is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. Although the syndrome had been described thousands of years before, it was named after John Langdon Down who described ...

Spermatogonial Stem Cells: Biology, Isolation, Culture, Characterization, and Practical Perspectives

Spermatogonial stem cells (SSCs) also known as germ stem cells (GSCs) are the basis of spermatogenesis process in the testis. Furthermore, they are also valuable cells with different applications in developmental biology, transgenesis technology, and clinic. Understanding the new findings related to the cell and molecular biology of SSCs and the methods for isolation and maintenance of these ce...