Pramipexole Upregulates Dopamine Receptor D2 and D3 Expression in Rat Striatum
نویسندگان
چکیده
منابع مشابه
Differential aging-related changes of D1, D2, and D3 dopamine receptor expression in the striatum
Aging is associated with a decrease in motor function and a concomitant increase in muscle stiffness and tone. The striatum plays a critical role in the control of motor function, and it receives strong dopamine (DA) innervation from the substantia nigra. DA actions are mediated by both excitatory D1-like (D1 and D5) and inhibitory D2-like (D2, D3, and D4) receptors, and D1, D2, and D3 receptor...
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The construct of impulsivity is considered as a major trait of personality. There is growing evidence that the mesolimbic dopamine system plays an important role in the modulation of impulsivity and venturesomeness, the two key components within the impulsivity-construct. The aim of the present study was to explore an association between trait impulsivity measured with self-assessment and the d...
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Dopamine (DA) is one of the main catecholamines in the brain and is crucial for movement coordination, endocrine function, reward, mood, memory and emotions. The dopaminergic system is the primary therapeutic target in the treatment of Parkinson’s disease (PD), drug addiction and schizophrenia. Notwithstanding, dysfunction of central dopaminergic neurotransmission has also been associated to de...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2012
ISSN: 1347-8613,1347-8648
DOI: 10.1254/jphs.12096sc