Pre-treatment with dexamethasone attenuates experimental ventilator-induced lung injury

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Pre-treatment with dexamethasone attenuates experimental ventilator-induced lung injury.

OBJECTIVE To evaluate the effects that administering dexamethasone before the induction of ventilator-induced lung injury (VILI) has on the temporal evolution of that injury. METHODS Wistar rats were allocated to one of three groups: pre-VILI administration of dexamethasone (dexamethasone group); pre-VILI administration of saline (control group); or ventilation only (sham group). The VILI was...

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ژورنال

عنوان ژورنال: Jornal Brasileiro de Pneumologia

سال: 2016

ISSN: 1806-3713

DOI: 10.1590/s1806-37562015000000350