Precision Polymers

Precision synthesis, structure and function of helical polymers

Helical structures are chiral, which means that if we can synthesize a polymer having a stable one-handed helicity, the polymer is optically active. In 1979, we succeeded in the synthesis of a one-handed helical polymer from an optically inactive achiral monomer, triphenylmethyl methacrylate (TrMA). This is the first example of the asymmetric synthesis of an optically active one-handed helical ...

Precision medicine, technologies, and molecular diagnostics

Introduction: Genetics, cellular and molecular medicines are cutting-edge sciences and technologies that play an important role in improving human health and quality of life. In addition, medical and biological sciences have clearly shown that the onset of diseases differs from person to person due to their different genetic profiles and variations in molecular basis. Therefore, it is feasible ...

Precision Chemistry for Precision Medicine

During the 2015 State of the Union address, President Obama unveiled plans for a $215 million Precision Medicine Initiative. The details of this plan were laid out by past and present directors of the National Institutes of Health, Harold Varmus and Francis Collins, in a commentary in the New England Journal of Medicine. While the announcement stood as a public statement of support for funding,...

From Commodity Polymers to Functional Polymers

Functional polymers bear specified chemical groups, and have specified physical, chemical, biological, pharmacological, or other uses. To adjust the properties while keeping material usage low, a method for direct synthesis of functional polymers is indispensable. Here we show that various functional polymers can be synthesized by in situ cross-linked polymerization/copolymerization. We demonst...

AccucheckInform II: About Its Accuracy and Precision