Predictors of adverse outcome of severe infections in critically ill children

Background. Assessing the probability of an adverse outcome severe infections and sepsis in children order to timely correct treatment is one most acute problems resuscitation intensive care. The ojective was identify predictors upon admission ICU. Materials methods. Design – a retrospective cohort multicenter uncontrolled study. 180 with course infectious diseases were examined. mean age patients 1.3 (0.5–4.1) years, boys 94 (52.2 %) girls 86 (47.7 patients. Signs shock at detected 100 (55.6 children. PEMOD score on first day ICU 5.0 (40–8.0) points. duration 8.6 (1–83) days. Depending disease, all divided into two groups: groupI «recovery», group II «death». Results. Significant differences depending disease characteristic clinical laboratory signs such as bloodpressure, base deficiency, score, concentration total protein, albumin lactate blood. Mean blood pressure below 60 mmHg., deficiency > [–8.4] mmol/L, plasma greater than 3.3 serum less 30 g/L 7 indicate high death. magnitude has maximum sensitivity (87.5 specificity (61.3 predict admission. Conclusion. severity condition due phenomena systemic hypoperfusion, hypoxia metabolic disorders against background hypoalbuminemia.