Preparation and characterization of etoricoxib-β-cyclodextrin complexes prepared by the kneading method
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Preparation and characterization of etoricoxib-beta-cyclodextrin complexes prepared by the kneading method.
The binary system of etoricoxib with beta-cyklodextrin (beta-CD) was prepared by the kneading method. Drug-cyclodextrin interactions in solution were investigated by the phase solubility analysis. Differential scanning calorimetry, infrared spectroscopy, powder X-ray diffractometry and microscopic study were used to characterize the solid state of all binary systems, whereas their dissolution p...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2007
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-007-0028-2