Probabilistic analysis of activation volumes generated during deep brain stimulation
نویسندگان
چکیده
منابع مشابه
Probabilistic analysis of activation volumes generated during deep brain stimulation
Deep brain stimulation (DBS) is an established therapy for the treatment of Parkinson's disease (PD) and shows great promise for the treatment of several other disorders. However, while the clinical analysis of DBS has received great attention, a relative paucity of quantitative techniques exists to define the optimal surgical target and most effective stimulation protocol for a given disorder....
متن کاملTissue and electrode capacitance reduce neural activation volumes during deep brain stimulation.
OBJECTIVE The growing clinical acceptance of neurostimulation technology has highlighted the need to accurately predict neural activation as a function of stimulation parameters and electrode design. In this study we evaluate the effects of the tissue and electrode capacitance on the volume of tissue activated (VTA) during deep brain stimulation (DBS). METHODS We use a Fourier finite element ...
متن کاملO10: Deep Brain Stimulation and Psychiatry
The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette’s syndrome and major depression. This presentat...
متن کاملDeep brain stimulation activation volumes and their association with neurophysiological mapping and therapeutic outcomes.
OBJECTIVE Despite the clinical success of deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD), little is known about the electrical spread of the stimulation. The primary goal of this study was to integrate neuroimaging, neurophysiology and neurostimulation data sets from 10 patients with PD, unilaterally implanted with subthalamic nucleus (STN) DBS electrodes, to identif...
متن کاملVisualization for Understanding Uncertainty in Activation Volumes for Deep Brain Stimulation.
We have created the Neurostimulation Uncertainty Viewer (nuView or νView) tool for exploring data arising from deep brain stimulation (DBS). Simulated volume of tissue activated (VTA), using clinical electrode placements, are recorded along with patient outcomes in the Unified Parkinson's disease rating scale (UPDRS). The data is volumetric and sparse, with multi-value patient results for each ...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2011
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2010.10.059