Production of Pigments under Submerged Culture through Repeated Batch Fermentation of Immobilized Talaromyces atroroseus GH2

Pigments of natural origin have become a research trend, and fungi provide readily available alternative source. Moreover, developing novel processes that increase yields, reduce process time simplify downstream processing is increased interest. In this sense, work proposes an for Talaromyces atroroseus GH2 biomass re-utilization to produce pigments through consecutive batches using immobilized mycelium. Different support materials were evaluated pigment production immobilization capacity. Then, Taguchi’s method was applied determine the effect four factors related fungal (inoculum concentration, density, working volume volume). Afterward, kinetics cells T. in evaluated. All significant affected microorganism growth differently. At improved conditions, capacity reached 99.01 ± 0.37% 30% higher than free cells. Process showed could continue three limited by excessive growth. Indeed, more studies are still needed, but represents promising strategy allowing downstream-processing intensification since easily removed from fermentation media, thus paving way further development continuous process.