Prof. Yun Fan: persistence guarantees expertise, patience conquers difficulties

How Foreign Function Integration Conquers Conquers Heterogeneous Query Processing

With the emergence of application systems which encapsulate databases and related application components, pure data integration using, for example, a federated database system is not possible anymore. Instead, access via predefined functions is the only way to get data from an application system. As a result, retrieval of such heterogeneous and encapsulated data sources needs the combination of...

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Patience

What is patience? Humans and other animals often make decisions that trade off present and future benefits. Should a monkey eat an unripe fruit or wait for it to ripen? Should I purchase the iPhone at its debut or wait for the price to drop in a few months? In these dilemmas, large gains often require long waits, so decision makers must choose between a smaller, sooner reward and a larger, late...

Myc conquers all

or raft proteins, direct delivery is not the travel route of choice, according to Roman Polishchuk, Jennifer Lippincott-Schwartz (NIH, Bethesda, MD), and colleagues. They find that, contrary to earlier evidence, glycosyl phosphatidyl-inositol (GPI)–anchored raft proteins make a detour to the basolateral membrane of polarized MDCK cells before crossing the cell to their final destination in the ...

LOV conquers (sm)All GTPases

Knowledge of spatial patterning of GTPases is critical to understanding protein function since subcellular localization is essential for normal protein function. In this paper, we discuss how Hahn's group has created a new type of genetically encoded, light-activated enzyme that allows precise temporal and spatial control of the small GTPase, Rac1. This reagent enables this group to analyze the...