Programmable intracellular DNA biocomputing circuits for reliable cell recognitions
نویسندگان
چکیده
منابع مشابه
Circuits and programmable self-assembling DNA structures.
Self-assembly is beginning to be seen as a practical vehicle for computation. We investigate how basic ideas on tiling can be applied to the assembly and evaluation of circuits. We suggest that these procedures can be realized on the molecular scale through the medium of self-assembled DNA tiles. One layer of self-assembled DNA tiles will be used as the program or circuit that leads to the comp...
متن کاملWhole-cell biocomputing.
The ability to manipulate systems on the molecular scale naturally leads to speculation about the rational design of molecular-scale machines. Cells might be the ultimate molecular-scale machines and our ability to engineer them is relatively advanced when compared with our ability to control the synthesis and direct the assembly of man-made materials. Indeed, engineered whole cells deployed in...
متن کاملAutomated design of programmable enzyme-driven DNA circuits.
Molecular programming allows for the bottom-up engineering of biochemical reaction networks in a controlled in vitro setting. These engineered biochemical reaction networks yield important insight in the design principles of biological systems and can potentially enrich molecular diagnostic systems. The DNA polymerase-nickase-exonuclease (PEN) toolbox has recently been used to program oscillato...
متن کاملBiocomputing: DNA computes a square root.
465 news & views of amplifiers and logic devices based on graphene, actually enables a new class of nonlinear radiofrequency electronic devices. Frequency multipliers 5,6, , high-frequency mixers 7 and digital modulators 8,9 have all been recently demonstrated using this principle, with operating frequencies as high as 16 GHz and radiofrequency efficiencies in excess of 90% (ref. 10). Infrared ...
متن کاملInternal Testing of Programmable Circuits
The growing use of programmable circuits has made it necessary to perform accurate debug and internal testing of these circuits. To meet this challenge, we have developed an innovative method to investigate the internal functionality of programmable circuits.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Science
سال: 2019
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c8sc05217d