Progression on Oxidative Decyanation Approaches from Secondary Nitriles to Ketones and α‐Aminonitriles to Amides

The functional group transformation associated with nitrile moiety is considered a diligent research topic in the synthetic community as it building block for several organic molecules, including ketones and amides. Many methodologies have been developed synthesizing amides, considering them analogues exciting biological properties. However, there are limited articles to synthesize these important classes of compounds via oxidative decyanation nitriles α‐aminonitriles. As protocols decyanation, base‐induced functionality oxo carbanion formation an effective but under‐explored area research. In this context, we wish present outline studies secondary α‐aminonitriles afford corresponding amides since its inception.