Progressive Axonal Dysfunction Precedes Development of Neuropathy in Type 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Progressive Axonal Dysfunction Precedes Development of Neuropathy in Type 2 Diabetes
To evaluate the development of diabetic neuropathy, the current study examined changes in peripheral axonal function. Nerve excitability techniques were undertaken in 108 type 2 diabetic patients with nerve conduction studies (NCS), HbA(1c) levels, and total neuropathy score (TNS). Patients were categorized into two cohorts: patients with diabetes without neuropathy (DWN group [n = 56]) and pat...
متن کاملUncovering sensory axonal dysfunction in asymptomatic type 2 diabetic neuropathy
This study investigated sensory and motor nerve excitability properties to elucidate the development of diabetic neuropathy. A total of 109 type 2 diabetes patients were recruited, and 106 were analyzed. According to neuropathy severity, patients were categorized into G0, G1, and G2+3 groups using the total neuropathy score-reduced (TNSr). Patients in the G0 group were asymptomatic and had a TN...
متن کاملSexual Dysfunction in Women with Type 2 Diabetes Mellitus
Background: Sexual dysfunction (SD) is one of the important problems in diabetic patients.The present study aimed to determine the prevalence of sexual problems in Iranian women with type 2 diabetes mellitus. Methods: A cross-sectional study was conducted among type 2 diabetic women who visited two outpatient endocrine clinics, namely Imam Hospital and Tuba clinic (Sari, Iran) in 2012. Patients...
متن کاملThe Risk Factors in Serum of Peripheral Neuropathy Diabetic and Type 2 Diabetes Patients
Aims: The study's purpose was to evaluate the serious risk factor for the neuropathy disease in patients with diabetes Material & Methods: This research was done on 120 subjects classified into 40 with DPN T2DM and 40 with T2DM and 40 healthy considered as a control. As the conditions of the Iraqi Ministry of Health to evaluate the thesis clinically, that the number of samples examined should ...
متن کاملAxonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral Sclerosis
Wide-spread fasciculations are a characteristic feature in amyotrophic lateral sclerosis (ALS), suggesting motor axonal hyperexcitability. Previous excitability studies have shown increased nodal persistent sodium conductances and decreased potassium currents in motor axons of ALS patients, both of the changes inducing hyperexcitability. Altered axonal excitability potentially contributes to mo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diabetes
سال: 2012
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db11-1509