Progressive lower extremity weakness as the initial presentation of isolated large thoracic plasmacytoma

Plasmacytoma is a tumor of monoclonal plasma cells bone or soft tissue that can occur anywhere in the body without evidence systemic multiple myeloma. It may present as solitary masses and classified osseous if arising from extraosseous tissue. Osseous plasmacytoma most common form with predominance active hematopoietic bones, including vertebrae, femur, pelvis, ribs. The diagnosis made biopsy. Different imaging modalities allow for localization, magnetic resonance (MRI) gold standard to detect spinal cord compression. Corticosteroids provide analgesia, reduce vasogenic edema, have anti-myeloma activity which result better neurological outcomes cases acute should be started promptly once compression suspected. We report case progressive lower extremity weakness initial presentation thoracic plasmacytoma. patient was on high-dose corticosteroid after Magnetic confirmed T1-T2 corpectomy C5-T5 posterior fusion decompression stabilization done. He successfully discharged an inpatient rehabilitation facility plans definitive radiotherapy. Worsening back pain elderly patients raise concerns Early intervention relieve crucial preserve functions.
 
 Keywords: plasmacytoma, weakness, steroids, myeloma