Proinflammatory Vascular Calcification
نویسندگان
چکیده
منابع مشابه
Proinflammatory vascular calcification.
Vascular calcification occurs as part of atherosclerosis. It is caused by the deposition of basic calcium phosphate (BCP) crystals in what appears to be a highly regulated process resembling bone formation.1–4 Vascular calcification occurs in several forms,1–4 including small crystal deposits in the neointima and large calcified areas in more advanced atherosclerotic plaques, which frequently t...
متن کامل[Vascular calcification in CKD].
As doenças cardiovasculares (DCV) constituem a principal causa de mortalidade em pacientes com doença renal crônica (DRC).1 O risco de óbito por DCV nessa população chega a ser 10 a 30 vezes maior que aquele observado na população geral. Esse aumento da mortalidade também ocorre em pacientes nos estágios precoces da DRC,2 assim como naqueles submetidos a transplante renal.3 A alta prevalência d...
متن کاملMagnesium Counteracts Vascular Calcification
Cardiovascular disease is the leading cause of mortality in patients with chronic kidney disease (CKD). Cardiovascular events are 5 to 30× more likely to occur in end-stage renal disease (ESRD) patients compared with the general population of the same age, sex, and race. In dialysis patients, arterial stiffness has been identified as an independent risk factor for cardiovascular mortality. An i...
متن کاملVascular calcification mechanisms.
Vascular calcification is highly correlated with cardiovascular disease mortality, especially in patients with ESRD or diabetes. In addition to the devastating effects of inappropriate biomineralization seen in cardiac valvulopathies, calciphylaxis, and idiopathic arterial calcification, vascular calcification is now recognized as a marker of atherosclerotic plaque burden as well as a major con...
متن کاملGenetics of vascular calcification.
Recessive mutations in the NTE5 gene were recently described in lower-extremity vascular calcification. ENPP1 mutations were previously described in a severe disorder of vascular calcification in infancy. Together these data support that extracellular adenosine and pyrophosphate are essential components of the pathways in vascular disease. Arterial calcification by impairing blood flow and redu...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2005
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000172407.20974.e5