Proliferative Activity in Barrett’s Esophagus Before and After Antireflux Surgery

Barrett's esophagus and antireflux surgery: wraps, rings, and HALOs.

To the Editor: W e read with interest the article by Reveiller et al,1 which was published in a recent issue of the Annals of Surgery. The genetic studies compared the effects of bile and acid on squamous and columnar epithelial cells of the esophagus, thus remodeling gastroesophageal reflux disease at the cellular level. The authors found that the major compounds of reflux, that is, bile and a...

Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive features.

BACKGROUND To investigate the factors leading to histologic regression of metaplastic and dysplastic Barrett's esophagus (BE). STUDY DESIGN The study sample consisted of 91 consecutive patients with symptomatic Barrett's esophagus. Pre- and posttreatment endoscopic biopsies from 77 Barrett's patients treated surgically and 14 treated with proton pump inhibitors (PPI) were reviewed. An expert ...

Postoperative symptoms and failure after antireflux surgery.

BACKGROUND Outcomes in patients having surgery for gastroesophageal reflux disease are most commonly determined by symptomatic assessment. Objective testing is usually reserved for symptomatic patients. HYPOTHESIS To evaluate the relationship between symptomatic and objective outcomes after antireflux surgery. DESIGN Retrospective analysis of prospectively collected data. SETTING A tertia...

Recall Activity: What Happens before and after Basal Cell Carcino-mas’ Surgery?

Failed antireflux surgery: results after reoperation.

BACKGROUND Since laparoscopy has become a common surgical approach for antireflux surgery, little is known regarding reoperation for failed antireflux surgery. METHODS Records of all patients who underwent reoperation without esophageal resection for symptoms of recurrent gastroesophageal reflux disease or hiatal hernia between July 1, 1995 and April 1, 2004 were reviewed. There were 126 pati...