Proliferative capacity of corneal endothelial cells
نویسندگان
چکیده
منابع مشابه
Comparison of proliferative capacity of genetically-engineered pig and human corneal endothelial cells.
PURPOSE The possibility of providing cultured corneal endothelial cells (CECs) for clinical transplantation has gained much attention. However, the worldwide need for human (h) donor corneas far exceeds supply. The pig (p) might provide an alternative source. The aim of this study was to compare the proliferative capacity of CECs from wild-type (WT) pigs, genetically-engineered (GE) pigs, and h...
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The process of wound healing of rabbit corneal endothelium involves the desquamation of significant numbers of endothelial cells, which may be found floating freely in the aqueous. It is suggested that this may be a general phenomenon of corneal endothelial wound healing, which accompanies the release of endothelial-cell attachments to Descemet's membrane and to neighboring cells during mitosis...
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PURPOSE To compare the effect of epidermal growth factor (EGF), nerve growth factor (NGF), platelet-derived growth factor-BB (PDGF-BB), bovine pituitary extract, and fetal bovine serum (FBS), alone or in combination, on proliferation of human corneal endothelial cells (HCEC) cultured from young (<30 years old) and older donors (>50 years old). METHODS Corneas from donors 2 to 79 years old wer...
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Logistic regression methods were used to analyse the influence of donor and storage factors on the quality of c~meas stored by organ culture in the Bristol eve bank in 1991. Averaae donor a(18 was 57 vears fsd 22. n=2770) -and time from death to en~cleation v& 8 hours (&I 7, n&782): Corneas were placed into organ culture within 27 houra (sd 10, n+2550) of donor death and were stored for 22 days...
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This article describes an algorithm for defining the precise, objective, repeatable and unambiguous segmentation of cells in images of the corneal endothelium. This issue is important for clinical purposes, because the quality of the grid cells is assessed on the basis of segmentation. Other solutions, including commercial software, do not always mark cell boundaries along lines of lowest brigh...
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ژورنال
عنوان ژورنال: Experimental Eye Research
سال: 2012
ISSN: 0014-4835
DOI: 10.1016/j.exer.2011.08.014