Prolonged hyperinsulinaemic hypoglycaemia in newborns with intrauterine growth retardation

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Cytokines in the Placenta of Pakistani Newborns with and with and without Intrauterine Growth Retardation

Background: Intrauterine growth retardation (IUGR) is major risk factor for increased neonatal mortality and morbidity, with a considerable risk for permanent brain damage. The prevalence of IUGR in Pakistan 1 newborns has been reported as high as 15-24%. The mechanism behind this condition remains unclear. It has been shown that cytokines play an important role in reproductive events. In the p...

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Intrauterine growth retardation.

The recognition that some low birthweight babies (<2500 g) were the victims of intrauterine growth retardation rather than premature birth was a milestone in perinatal medicine.'3 Up to 10% of all liveborn babies and at least 30% of those of low birth weight suffer from intrauterine growth retardation; their perinatal mortality is four to 10 times higher than that of normally grown babies-both ...

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Intrauterine Growth Retardation

Intrauterine growth retardation (IUGR) refers to fetal growth that has been constrained in utero. It results in newborns that have not attained their full growth potential and are already malnourished at birth. Fetuses that suffer from growth retardation have higher perinatal morbidity and mortality and are more likely to experience poor cognitive development and neurologic impairment during ch...

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Hyperinsulinaemic hypoglycaemia in preterm neonates.

Hyperinsulinism in infancy (HI) is an important cause of severe and recurrent hypoglycaemia in newborn infants. It usually appears in infants born at term, and only one case of its occurrence in a prematurely born infant has been reported as an incidental finding. This is a report of seven infants born at 31-36 weeks gestation who experienced severe persistent hyperinsulinism. Two infants were ...

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Prolonged elimination of tolbutamide in a premature newborn with hyperinsulinaemic hypoglycaemia.

So far, gestational diabetes treated with tolbutamide has never been associated with severe hypoglycaemia in the newborn when the mother's diabetes was well controlled. We report a case of a premature neonate, gestational age 34 weeks, with severe and long-standing hypoglycaemia from birth. The mother had well-controlled gestational diabetes, treated with tolbutamide from the 24th week of gesta...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition

سال: 2006

ISSN: 1359-2998,1468-2052

DOI: 10.1136/adc.2006.095919