Prolonged intravenous instead of oral antibiotics for acute hematogenous osteomyelitis in children

Comparative effectiveness of intravenous vs oral antibiotics for postdischarge treatment of acute osteomyelitis in children.

IMPORTANCE Postdischarge treatment of acute osteomyelitis in children requires weeks of antibiotic therapy, which can be administered orally or intravenously via a peripherally inserted central catheter (PICC). The catheters carry a risk for serious complications, but limited evidence exists on the effectiveness of oral therapy. OBJECTIVE To compare the effectiveness and adverse outcomes of p...

[Treatment of acute hematogenous osteomyelitis in children].

Experience in treatment of 348 children with acute hematogenic osteomyelitis is analysed. Newborn infants and children whose ages ranged from 1 to 15 years formed a group of patients. Of decisive importance in the outcome of the disease are early diagnosis and emergency operative measures, aimed at decompressing, opening and cleansing the purulent foci, producing a high concentration of antibio...

Prolonged intravenous therapy versus early transition to oral antimicrobial therapy for acute osteomyelitis in children.

OBJECTIVES Early transition from intravenous to oral antimicrobial therapy for acute osteomyelitis in children has been suggested as a safe and effective alternative to traditional prolonged intravenous therapy via central venous catheter, but no studies have directly compared these 2 treatment modalities. We sought to compare the effectiveness of early transition from intravenous to oral antim...

Acute hematogenous osteomyelitis.

Oral vs. Intravenous Antibiotics for the Treatment of Acute Bacterial Osteomyelitis in the Veteran Population

Christian Chidiac, MD, PhD and Florent Valour, MD, PhD; Inserm 1111, UCBL1, Hospices Civils de Lyon, Lyon, France, ID Department, Regional Reference Center for Bji, Hospices Civils de Lyon, Lyon, France, Laboratory of Bacteriology, Regional Reference Center for Bji, Hospices Civils de Lyon, Lyon, France, Laboratory ID Department, Regional Reference Center for Bji, Hospices Civils de Lyon – Hôpi...