Prostaglandins and the cardiovascular system.
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چکیده
منابع مشابه
[Prostaglandins and the cardiovascular system].
Prostaglandins have been known for a long time to have a vaso-active action. The recent discovery that prostacycline or thromboxane A2 have a greater vascular action than the prostaglandins suggests that these substances may have a physiological or pathological role, for example in endotoxin shock, anaphylaxis, coronary thrombosis, chronic hypertension, etc. The discovery of the leukotrienes an...
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PROSTAGLANDINS (PGs) are natural constituents of the brain and spinal cord. They are released from the central nervous system (CNS) spontaneously, in response to electrical and chemical stimulation and during fever. In addition to their action on brain-stem neurones when applied iontophoretically (Avanzino, Bradley and Wolstencroft, 1966) they have potent CNS effects which are now considered. B...
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One of the goals of medicinal chemistry research and drug discovery is to provide a rationalbasis for the design of new medicinal agents. Organic compounds and their reactions have beenutilized by people since antiquity. Due to the increasing demand for bioactive molecules, organicchemists are increasingly required to synthesize new compounds of biological interest. AsBenzimidazoles are very us...
متن کامل[Prostaglandins in the cardio-vascular system].
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متن کاملProstaglandins, antidiuretic hormone and renin angiotensin system.
Current knowledge on prostaglandin biosynthesis is reviewed, centering on how PGs participate in the regulation of vascular tone and the prevention of platelet deposition on endothelial surfaces. Discussion includes review of the vasoactivity of the PG endoperoxides, thromboxane, prostacyclin, and prostaglandin E2; prostaglandin-catabolizing enzymes; polyunsaturated fatty acid precursors; nutri...
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ژورنال
عنوان ژورنال: Heart
سال: 1983
ISSN: 1355-6037
DOI: 10.1136/hrt.49.5.405