Protective effects of endothelin antagonists in chronic renal failure
نویسندگان
چکیده
منابع مشابه
Differential effects of endothelin-1 antagonists on erythropoietin-induced hypertension in renal failure.
Recently, it was reported that blood vessel immunoreactive endothelin-1 (irET-1) content is increased in hypertensive uremic rats treated with recombinant human erythropoietin (rhEPO). The present study was designed to evaluate whether ET-1 receptor blockade can prevent the progression of hypertension in renal failure rats receiving rhEPO and, if so, whether selective ET(A) and nonselective ET(...
متن کاملChronic Renal Failure and Its effects on Serum Lipids
Background: Metabolic disturbances and dyslipidemia are among the most important medical problems in human society. Their effects on the mortality of coronary heart disease (CHD) have lead to many investigations about them. Materials and Methods: An epidemiologic cross-sectional study was carried out on 10136 persons selected randomly in Tehran urban district 13 with a minimum age of 20 years ...
متن کاملEndothelin in renal disease: role of endothelin antagonists.
In spite of tremendous progress in the understanding of human disease, the search for new mediators continues as numerous conditions remain poorly understood. In particular in many forms of renal disease, effective and cause-orientated forms of therapy are still lacking. The discovery of new pathogenetic mechanisms often leads to the development of new drugs with previously unknown properties w...
متن کاملProtective Effects of Crocin against Cisplatin-Induced Acute Renal Failure and Oxidative Stress in Rats
Background. The major side effect of cisplatin, used in some tumours, is nephrotoxicity. Reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. The main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. Methods. In this study, animal...
متن کاملAssociation of hemodialysis and pruritus in chronic renal failure
Background and aim: Pruritus is a common disabling problem in patients with end stage renal disease. Several studies has recorded the relation between pruritus with hemodialysis in chronic renal failure (CRF) patients. This study was designed to evaluate the effect of hemodialysis on pruritus of patients with CRF.Materials and Methods: After recording the demographic data and the diagnosis of d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 1999
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/14.suppl_4.29