Protective Effects of Molsidomine Against Cisplatin-Induced Nephrototoxicity*

Protective Effects of Boswellia Thurifera Aqueous Extract against Cisplatin-Induced Cytotoxicity on Sperm Quality in Mice

Introduction: Cisplatin (CIS) is among the chemotherapeutic agent. However, its use is limited due to side effects, such as impairment in the spermatogenesis process. On the other hand, Boswellia Thurifera has protective effects on the reproductive system. Therefore, the present study aimed to investigate the protective effect of Boswellia Thurifera aqueous extract against cisplatin-induced cyt...

Protective Effects of Crocin against Cisplatin-Induced Acute Renal Failure and Oxidative Stress in Rats

Background. The major side effect of cisplatin, used in some tumours, is nephrotoxicity. Reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. The main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. Methods. In this study, animal...

Protective effects of molsidomine against doxorubicin-induced renal damage in rats.

PURPOSE The purpose of this study was to investigate the therapeutic and protective effects of molsidomine (MLS) against doxorubicin (DOX)-induced renal damage in rats. METHODS Forty rats were randomly divided into five groups (control, MLS, DOX, DOX+MLS and MLS+DOX groups). Thiobarbituric acid reactive substance (TBARS), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), ...

protective effect of dietary walnut against cisplatin - induced neurotoxicity

Protective Effect of Aqueous and Ethanolic Extracts of Portulaca Oleracea Against Cisplatin Induced Nephrotoxicity

Objective(s) Portulaca oleracea L. is a herbaceous weed from portulacaceae family. It can be found in many parts of the world. Modern pharmacological studies have demonstrated that P. oleracea have antioxidant effects. The protective effect of aqueous and ethanolic extract of P. oleracea against cisplatin-induced renal toxicity was studied in rats. Materials and Methods Single intraperitonea...