Protein structure prediction
نویسندگان
چکیده
منابع مشابه
Bayesian Protein Structure Prediction
An important role for statisticians in the age of the Human Genome Project has developed in the emerging area of “structural bioinformatics”. Sequence analysis and structure prediction for biopolymers is a crucial step on the path to turning newly sequenced genomic data into biologically and pharmaceutically relevant information in support of molecular medicine. We describe our work on Bayesian...
متن کاملProtein Structure Prediction
Protein structure prediction from sequence remains a premiere computational problem for modern molecular biology. The papers in this session address ab initio folding simulations and theoretical studies, the use of known structures as a basis for prediction, and analysis of how and what we know (or don't) about those known structures. The \thermodynamic hypothesis" asserts that proteins fold to...
متن کاملProtein secondary structure prediction.
The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family. New techniques that apply machine learning and discriminant analysis show promise as alternatives to neural networks.
متن کاملPrediction of protein structure
Proteins build their three-dimensional structures from the bottom up, utilizing bonding interactions between atoms in the backbone, the sidechains and water. And they do it with astonishing speed and efficiency. Although protein chemists would love to understand and model protein folding at this detailed level of physical chemistry, it is simply too formidable a challenge — now and for the fore...
متن کاملProtein Structure Prediction Ii
Jeffrey Skolnick ,2 Yang Zhang Because the molecular function of a protein depends on its three dimensional structure, which is often unknown, protein structure prediction is an essential tool in proteomics. The state of the art of protein structure prediction is reviewed with emphasis on knowledge-based comparative modeling/threading approaches that exploit the observation that the protein dat...
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ژورنال
عنوان ژورنال: International Journal of Modern Physics B
سال: 2018
ISSN: 0217-9792,1793-6578
DOI: 10.1142/s021797921840009x