Protocol biopsy and subclinical rejection in patients after kidney transplantation treated by tacrolimus (Prograf)

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Protocol biopsy and subclinical rejection in patients after kidney transplantation treated by tacrolimus (Prograf).

The article deals with the contribution of tacrolimus (Prograf) to improvement in kidney transplant results. Tacrolimus, in comparison with cyclosporine significantly reduces the incidence of acute rejection and improves survival of grafts as well as patients. Based on the literature, the primary immunological differences between tacrolimus and cyclosporine effects are pointed out. These differ...

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Tacrolimus and diabetic ketoacidosis after kidney transplantation in a 15-year-old girl (Case Report)

Tacrolimus is a main drug for induction and maintenance immunosuppression for patients with kidney transplants in many centers. One of important side effect of drug is post-transplant diabetes mellitus. Of course, diabetes ketoacidosis (DKA) is rare. In this report, a 12-year-old girl with DKA was presented after 45 days of kidney transplantation. 

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Statin therapy for preventing cardiovascular diseases in patients treated with tacrolimus after kidney transplantation

Background Lipid abnormalities are prevalent in tacrolimus-treated patients. The aim of the study was to evaluate the preventive effects of statin therapy on major adverse cardiovascular events (MACE) in patients treated with tacrolimus-based immunosuppression after kidney transplantation (KT), and to identify the risk factors. Methods This observational cohort study included adult patients w...

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Increased early rejection rate after conversion from tacrolimus in kidney and pancreas transplantation.

CONTEXT A successful immunosuppression regimen for combined kidney and pancreas transplants is tacrolimus, mycophenolate mofetil, and prednisone. However, not all patients tolerate these immunosuppressants especially tacrolimus. OBJECTIVE To evaluate the efficacy of cyclosporine as a rescue agent for tacrolimus toxicity in combined kidney and pancreas transplants. DESIGN Retrospective. SE...

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Immunosuppression with tacrolimus early after orthotopic heart transplantation: a comparison of prograf and advagraf.

BACKGROUND We compared trough levels and clinical outcomes in patients who received Prograf or Advagraf (tacrolimus) de novo following heart transplantation surgery. METHODS Eighty-two patients were included in this follow-up study. Biopsy results were controlled for the first 3 months after orthotopic heart transplantation. Trough levels were monitored for 4 weeks: daily during the first 7 d...

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ژورنال

عنوان ژورنال: Biomedical Papers

سال: 2003

ISSN: 1213-8118,1804-7521

DOI: 10.5507/bp.2003.028