PS-209 Bcg Vaccination Can Prevent Hyperoxic Lung Injury?
                    
                        
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                    چکیده
منابع مشابه
Hyperoxic acute lung injury.
Prolonged breathing of very high F(IO(2)) (F(IO(2)) ≥ 0.9) uniformly causes severe hyperoxic acute lung injury (HALI) and, without a reduction of F(IO(2)), is usually fatal. The severity of HALI is directly proportional to P(O(2)) (particularly above 450 mm Hg, or an F(IO(2)) of 0.6) and exposure duration. Hyperoxia produces extraordinary amounts of reactive O(2) species that overwhelms natural...
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Hyperoxic acute lung injury (HALI) refers to the damage to the lungs secondary to exposure to elevated oxygen partial pressure. HALI has been a concern in clinical practice with the development of deep diving and the use of normobaric as well as hyperbaric oxygen in clinical practice. Although the pathogenesis of HALI has been extensively studied, the findings are still controversial. Nitric ox...
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The effect of adverse perinatal environment (like maternal infection) has long-standing effects on many organ systems, including the respiratory system. Use of maternal nutritional supplements is an exciting therapeutic option that could be used to protect the developing fetus. In a recent issue of the journal, Ali and associates (Ali M, Heyob KM, Velten M, Tipple TE, Rogers LK. Am J Physiol Lu...
متن کاملBCG Vaccination
BCG VACCINATION. Studies by the WHO Tuberculosis Research Office, Copenhagen. Report prepared under the direction of Lydia B. Edwards and Carroll E. Palmer with the assistance of Knut Magnus. Monograph Series No. 12. Geneva, World Health Organization, 1953. 307 pp. 15/-, $3.00, Sw. fr. 12.This monograph contains the results of an inquiry into the variable factors that affect BCG vaccination. Th...
متن کاملMetallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.
Hypozincemia, with hepatic zinc accumulation at the expense of other organs, occurs in infection, inflammation, and aseptic lung injury. Mechanisms underlying zinc partitioning or its impact on extrahepatic organs are unclear. Here we show that the major zinc-binding protein, metallothionein (MT), is critical for zinc transmigration from lung to liver during hyperoxia and preservation of intrap...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 2014
ISSN: 0003-9888,1468-2044
DOI: 10.1136/archdischild-2014-307384.507