Pseudoknots in prion protein mRNAs confirmed by comparative sequence analysis and pattern searching
نویسندگان
چکیده
منابع مشابه
Pseudoknots in prion protein mRNAs confirmed by comparative sequence analysis and pattern searching.
The human prion gene contains five copies of a 24 nt repeat that is highly conserved among species. An analysis of folding free energies of the human prion mRNA, in particular in the repeat region, suggested biased codon selection and the presence of RNA patterns. In particular, pseudoknots, similar to the one predicted by Wills in the human prion mRNA, were identified in the repeat region of a...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2001
ISSN: 1362-4962
DOI: 10.1093/nar/29.3.753