Public Domain Databases for Medicinal Chemistry
نویسندگان
چکیده
منابع مشابه
Complementarity between public and commercial databases: new opportunities in medicinal chemistry informatics.
The last two years have seen a dramatic expansion in public cheminformatics, as exemplified by the approximate five-fold growth of PubChem from over 50 contributing data sources. Consequently, medicinal chemists who were hitherto limited to commercial databases now also have access to public sources that they can download and/or query directly over the Web. The range of public sources, particul...
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Since its first use in the steroid field in the late 1950s, the use of fluorine in medicinal chemistry has become commonplace, with the small electronegative fluorine atom being a key part of the medicinal chemist's repertoire of substitutions used to modulate all aspects of molecular properties including potency, physical chemistry and pharmacokinetics. This review will highlight the special n...
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Several lymphoma T cell lines differ in membrane superficial markers and do not respond to the same drugs and compounds. Tilia x viridis (Bayer) Simonk nothosubspecie moltkei (Dippel) Xifreda is a plant widely distributed in Argentina. The aim of this work was to study comparatively the effects of dichloromethane extract and isolated compounds on BW 5147 and on another T lymphoma cell line EL-4...
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229 © 2011 Johnson Matthey http://dx.doi.org/10.1595/147106711X592899 http://www.platinummetalsreview.com/ Edited by Gérard Jaouen (Ecole Nationale Superieure de Chimie de Paris, France) and Nils Metzler-Nolte (Ruhr-Universität Bochum, Germany), Topics in Organometallic Chemistry, Vol. 32, Springer, Berlin, Heidelberg, Germany, 2010, 291 pages, ISBN: 978-3-642-13184-4, £171.00, €189.95, US$259....
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ژورنال
عنوان ژورنال: Journal of Medicinal Chemistry
سال: 2012
ISSN: 0022-2623,1520-4804
DOI: 10.1021/jm300501t