QTL analysis of self-selected macronutrient diet intake: fat, carbohydrate, and total kilocalories
نویسندگان
چکیده
منابع مشابه
QTL analysis of self-selected macronutrient diet intake: fat, carbohydrate, and total kilocalories.
The present study investigated the inheritance of dietary fat, carbohydrate, and kilocalorie intake traits in an F(2) population derived from an intercross between C57BL/6J (fat-preferring) and CAST/EiJ (carbohydrate-preferring) mice. Mice were phenotyped for self-selected food intake in a paradigm which provided for 10 days a choice between two macronutrient diets containing 78/22% of energy a...
متن کاملHigh-Resolution Mapping of a Genetic Locus Regulating Preferential Carbohydrate Intake, Total Kilocalories, and Food Volume on Mouse Chromosome 17
The specific genes regulating the quantitative variation in macronutrient preference and food intake are virtually unknown. We fine mapped a previously identified mouse chromosome 17 region harboring quantitative trait loci (QTL) with large effects on preferential macronutrient intake-carbohydrate (Mnic1), total kilcalories (Kcal2), and total food volume (Tfv1) using interval-specific strains. ...
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We investigated macronutrient intake after intraventricular injection of galanin (GAL, 3 nmol/5 microl/rat) and/or serotonin (5-HT, 50 nmol/5 microl/rat) in self-selecting fasted rats with preferences for either carbohydrates or fats. GAL injection significantly increased carbohydrate and total intake in all rats irrespective of macronutrient preference, whereas 5-HT alone did not affect macron...
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Responses of inflammatory markers to a low-fat, high-carbohydrate diet: effects of energy intake.
BACKGROUND Inflammation contributes to atherogenesis. Dietary fats may be proinflammatory. OBJECTIVE The objective was to determine whether energy intake modulates the effects of low-fat, high-carbohydrate intakes on inflammatory markers. DESIGN Twenty-two healthy postmenopausal women with a mean (+/-SD) age of 61 +/- 11 y, who were not receiving hormone replacement therapy, were fed eucalo...
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2002
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00037.2002