Quantitation of Tolmetin by High-Performance Liquid Chromatography and Method Validation
نویسندگان
چکیده
منابع مشابه
Method Development and Validation of Carisoprodol and its Impurities by Ultra Violet-High Performance Liquid Chromatography
Ultraviolet-h igh performance liquid chromatographic (UV-HPLC) method was developed for the quantitation of carisoprodol and its impurities viz 2-methyl-2-propylpropane-1, 3-diyl d icarbamate (impurity-D) and N-isopropyl -2-methyl-2-propyl-3-hydroxy propyl carbamate (impurity-B) in active pharmaceutical ingredient. Validation of the method showed excellent sensitivity, selectivity, accuracy, pr...
متن کاملA Method Development and Validation of Rabeprazole Sodium (API) by High-Performance Liquid Chromatography
A simple and accurate methods to determine Rabeprazole sodium, in pure powder and tablet dosage form, were developed and validated using liquid chromatography (LC). The LC separation was achieved on a Inertsil ODS 3V, 150 x 4.6 mm, 5μ in the isocratic mode using buffer : acetonitrile (65 : 35, v/v), adjusted to pH 6.00 ± 0.05 with dilute KOH , as the mobile phase at a flow rate of 1.5 ml/min. t...
متن کاملA quick and easy high performance liquid chromatography method for evaluation of cefixime in human plasma
Cefixime is essential member of orally energetic third generation cephalosporin and has tremendous activity aligned with many pathogens. The virtual bioavailability of a newly industrial dispersible tablet as compared with a recognized identified formulation. A simple and available reversed-phase HPLC method with UV detection has been urbanized and validate for cefixime evaluate in human p...
متن کاملVortex-Assisted Inverted Dispersive Liquid-Liquid Microextraction of Naproxen from Human Plasma and Its Determination by High-Performance Liquid Chromatography
Extraction and determination of naproxen from human plasma were performed using Vortex-Assisted Inverted Dispersive Liquid-Liquid MicroExtraction (VA−IDLLME) and High-Performance Liquid Chromatography (HPLC). The parameters affecting extraction recovery such as type and volume of extraction and disperser solvents, pH of sample solution, stirring rate, extraction time and salt addition were ...
متن کاملIdentification and quantitation by high-performance liquid chromatography of mancozeb following derivatization by 1,2-benzenedithiol.
Ethylenebisdithiocarbamate (EBDC) fungicides are the most important class of organic fungicides and exhibit a high degree of carcinogenicity, mutagenicity, and neurotoxicity. For that reason, the safe application of these fungicides in practice requires a convenient method for their determination, applicable to biological fluids. We describe a high-performance liquid chromatography (HPLC) assay...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2003
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/41.7.381