Quantitative Gait Analysis Detects Significant Differences in Movement between Osteoarthritic and Nonosteoarthritic Guinea Pig Strains before and after Treatment with Flunixin Meglumine

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Quantitative Gait Analysis Detects Significant Differences in Movement between Osteoarthritic and Nonosteoarthritic Guinea Pig Strains before and after Treatment with Flunixin Meglumine

A computer-aided gait analysis system was used to contrast two guinea pig strains with differing propensity for osteoarthritis (OA), with/without administration of a nonsteroidal anti-inflammatory drug. Walking speed and static/dynamic gait parameters were determined at baseline. Flunixin meglumine was given and animals were evaluated 4, 24, and 72 hours after treatment. Body weight was compare...

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Differences in susceptibility to infection with Treponema pallidum (Nichols) between five strains of guinea pig.

Groups of 10 young male guinea pigs of inbred strains 2 and 13 and outbred strains Hartley A, Hartley B, and one deficient in the fourth component of complement (C4D) were infected intradermally with 80 X 10(6) Treponema pallidum (Nichols). The course of infection and production of antitreponemal antibody were examined. Strain C4D guinea pigs were the most susceptible to infection (100%); inbre...

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Toxicity of Flunixin Meglumine in Broiler Chickens

This study was designed to evaluate the toxicity of flunixin meglumine, a nonsteroidal anti-inflammatory drug which might serve as an alternate of diclofenac that has been shown to cause toxicity in vultures. Twenty five broiler chickens of five weeks of age were randomly divided into five equal groups and treated with flunixin meglumine at the dosage rate of 0, 1.25, 2.5, 5 and 10 mg/kg body w...

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ژورنال

عنوان ژورنال: Arthritis

سال: 2014

ISSN: 2090-1984,2090-1992

DOI: 10.1155/2014/503519