Quantitative study of solvent and surface effects on analyte ionization in desorption ionization on silicon (DIOS) mass spectrometry
نویسندگان
چکیده
منابع مشابه
Desorption/ionization on silicon (DIOS): a diverse mass spectrometry platform for protein characterization.
Since the advent of matrix-assisted laser desorption/ionization and electrospray ionization, mass spectrometry has played an increasingly important role in protein functional characterization, identification, and structural analysis. Expanding this role, desorption/ionization on silicon (DIOS) is a new approach that allows for the analysis of proteins and related small molecules. Despite the ab...
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Common to all experiments in mass spectrometry is the creation of gas-phase ions. Electron impact (EI) ionization is a familiar method for creating ions from volatile gas-phase molecules (M). In EI ionization, fast-moving electrons remove an electron from the neutral molecule to create the odd-electron molecular ion M`Õ. Another common ionization method is chemical ionization (CI). Here, an ion...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 2008
ISSN: 1044-0305,1879-1123
DOI: 10.1016/j.jasms.2007.10.002