Quantitative topographic imaging using a near-field scanning microwave microscope

Nondestructive Label-Free Mapping of DNA Bioassay Using a Near-Field Scanning Microwave Microscope

Near-field scanning microwave microscope (NSMM) is used to readout and visualize homemade 10mer oligonucleotides microarrays of DNA. NSMM instrumentation does not require labeling of target sequences with fluorophores or other tagging groups. Sensitive examination of DNA coverage and high resolution mapping of DNA spots in the microarray were observed by measuring the change of microwave reflec...

Transmission near-field scanning microscope for infrared chemical imaging

We report transmission infrared near-field scanning microscopy ~IR-NSOM! imaging of chemically amplified photoresist polymers patterned by ultraviolet exposure. Chemical specificity was attained using infrared wavelengths tuned to the 3 mm OH stretch absorption band of the polymer, a band sensitive to the chemical changes characteristic of the lithographic photochemical process of this material...

Cloaked near-field scanning optical microscope tip for noninvasive near-field imaging.

Near-field imaging is a well-established technique in biomedical measurements, since closer to the detail of interest it is possible to resolve subwavelength details otherwise unresolved by regular lenses. A near-field scanning optical microscope (NSOM) tip may indeed overcome the resolution limits of far-field optics, but its proximity inherently perturbs the measurement. Here, we apply the re...

Near-field Scanning Optical Microscope Platform

Scanning Near-field Raman Spectroscopic Microscope