Radiation, inflammation and the immune response in cancer
نویسندگان
چکیده
منابع مشابه
Radiation, Inflammation, and Immune Responses in Cancer
Chronic inflammation has emerged as one of the hallmarks of cancer. Inflammation also plays a pivotal role in modulating radiation responsiveness of tumors. As discussed in this review, ionizing radiation (IR) leads to activation of several transcription factors modulating the expression of numerous mediators in tumor cells and cells of the microenvironment promoting cancer development. Novel t...
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15 صفحه اولInnate immune cells in inflammation and cancer.
The innate immune system has evolved in multicellular organisms to detect and respond to situations that compromise tissue homeostasis. It comprises a set of tissue-resident and circulating leukocytes primarily designed to sense pathogens and tissue damage through hardwired receptors and eliminate noxious sources by mediating inflammatory processes. While indispensable to immunity, the inflamma...
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ژورنال
عنوان ژورنال: Mammalian Genome
سال: 2018
ISSN: 0938-8990,1432-1777
DOI: 10.1007/s00335-018-9777-0