Radiation resistance and stem-like cells in brain tumors
نویسندگان
چکیده
منابع مشابه
MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells
Glioblastoma (GBM) contains stem-like cells (GSCs) known to be resistant to ionizing radiation and thus responsible for therapeutic failure and rapidly lethal tumor recurrence. It is known that GSC radioresistance relies on efficient activation of the DNA damage response, but the mechanisms linking this response with the stem status are still unclear. Here, we show that the MET receptor kinase,...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2006
ISSN: 1535-6108
DOI: 10.1016/j.ccr.2006.11.008