Radix Dipsaci does not improve tendon healing in a rat model of patellar tendon donor site injury
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چکیده
منابع مشابه
Early voluntary exercise does not promote healing in a rat model of Achilles tendon injury.
Mechanical stress is an important modulator of connective tissue repair. However, the effects on tendon healing are very poorly defined, preventing optimal use of mechanical stress. We hypothesized that early voluntary exercise initially retards tendon repair but results in a faster recovery rate at longer term. Male Wistar rats were injured by a collagenase injection in the Achilles tendon, an...
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BACKGROUND AND PURPOSE Should blockade of TNF-α be avoided after orthopedic surgery? Healing of injuries in soft tissues and bone starts with a brief inflammatory phase. Modulation of inflammatory signaling might therefore interfere with healing. For example, Cox inhibitors impair healing in animal models of tendon, ligament, and bone injury, as well as in fracture patients. TNF-α is expressed ...
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Tendon lesions are among the most frequent musculoskeletal pathologies. Vascular endothelial growth factor (VEGF) is known to regulate angiogenesis. VEGF-111, a biologically active and proteolysis-resistant splice variant of this family, was recently identified. This study aimed at evaluating whether VEGF-111 could have a therapeutic interest in tendon pathologies. Surgical section of one Achil...
متن کاملEffect of tendon hydrogel on healing of tendon injury
Hand trauma arising from postoperative acute or chronic tendon injuries leads to delayed union and is one of the greatest challenges in clinical practice. The present study hypothesized that an extracellular matrix hydrogel made from tendons can promote tendon healing and improve tissue regeneration. To verify this, 36 Wistar rats were subjected to bilateral full-thickness injury of their Achil...
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INTRODUCTION: Prior research has examined complex methods of biologic augmentation during rotator cuff repair, including tendon transplants and extracellular matrix grafts. Our proposed procedure utilizes local autogenous bone marrow delivered to the repair site via a cannulated humeral implant. Such marrow delivery channels could be developed for suture anchors and other surgical hardware and ...
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ژورنال
عنوان ژورنال: Orthopaedic Surgery
سال: 2010
ISSN: 1757-7853,1757-7861
DOI: 10.1111/j.1757-7861.2010.00085.x