Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation
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Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation
Mouse embryonic endothelial progenitor cells (eEPCs) acquire a mature phenotype after treatment with cyclic adenosine monophosphate (cAMP), suggesting an involvement of Raf serine/threonine kinases in the differentiation process. To test this idea, we investigated the role of B-Raf and C-Raf in proliferation and differentiation of eEPCs by expressing fusion proteins consisting of the kinase dom...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2007
ISSN: 1582-1838,1582-4934
DOI: 10.1111/j.1582-4934.2007.00123.x