Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.
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چکیده
منابع مشابه
Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.
We have examined the incidence and size of infarction after occlusion of different portions of the rat middle cerebral artery (MCA) in order to define the reliability and predictability of this model of brain ischemia. We developed a neurologic examination and have correlated changes in neurologic status with the size and location of areas of infarction. The MCA was surgically occluded at diffe...
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Stroke is the leading cause of disability and the third leading cause of death in adults worldwide. In human stroke, there exists a highly variable clinical state; in the development of animal models of focal ischemia, however, achieving reproducibility of experimentally induced infarct volume is essential. The rat is a widely used animal model for stroke due to its relatively low animal husban...
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ژورنال
عنوان ژورنال: Stroke
سال: 1986
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.17.3.472