Reactions of Renal Dipeptidase and Cupric Ions with Unsaturated Dipeptides
نویسندگان
چکیده
منابع مشابه
Reactions of glycine-containing peptides with cupric ions and with p-nitrophenyl acetate.
The reactivity of groups in proteins may be studied in terms of their rates of reaction to form stable or unstable products or in terms of equilibria with small molecules or ions (2). The equilibria between cupric ions and peptides are of particular interest because of the stability and spectral properties of the complexes formed and the biological importance of the copper proteins. It has been...
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Titrations and spectral measurements of sperm whale metmyoglobin (2) and apomyoglobin (3) in the presence of cupric ion indicate that the metal ion may form chelates with imidazole groups and some other proton-bearing groups such as peptide amides. The titration and spectral properties of complexes of certain histidine-containing peptides have proved to be similar to those of the protein (4). A...
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The interaction of Cu2+ with isonicotinic acid hydrazide (INH) and some of its derivatives has been investigated by means of electron spin resonance, nuclear magnetic resonance, and optical absorption studies. It could be shown that an interaction exists between the metal ions and the hydrazine side chain in addition to the very weak interaction with the ring nitrogen. The results obtained indi...
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The reaction of a series of allyl-substituted bis(phenylsulfony1)methanes or dimethyl malonates with 2,3-bis(phenylsulfonyl)l13-butadiene in the presence of base afforded alkenyl-substituted allenes in good yield. The reaction proceeds by initial attack of the soft carbanion onto the terminal position of the diene and subsequent PhS02elimination to give the phenylsulfonyl substituted allene. Th...
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The effect of divalent cations on cell fusion by concentrated Sendai virus, inactivated by beta-propiolactone, was investigated using Vero and mouse L-929 cells in monolayers. With both cell lines, which are normally resistant to exogenous viral fusion, Cu(2+) in sublethal concentrations was found to promote polykaryon formation to a marked degree. The simultaneous presence of Cu(2+) and virus ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1967
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)96214-9