Reference-free quantification of EEG spectra: Combining current source density (CSD) and frequency principal components analysis (fPCA)

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Reference-free quantification of EEG spectra: combining current source density (CSD) and frequency principal components analysis (fPCA).

OBJECTIVE Definition of appropriate frequency bands and choice of recording reference limit the interpretability of quantitative EEG, which may be further compromised by distorted topographies or inverted hemispheric asymmetries when employing conventional (non-linear) power spectra. In contrast, fPCA factors conform to the spectral structure of empirical data, and a surface Laplacian (2-dimens...

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Current Source Density (CSD) Analysis

Current Source Density analysis (CSD) is a class of methods of analysis of extracellular electric potentials recorded at multiple sites leading to estimates of current sources generating the measured potentials. It is usually applied to low-frequency part of the potential (called the Local Field Potential, LFP) and to simultaneous recordings or to recordings taken with fixed time reference to t...

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Novelty P3 reductions in depression: characterization using principal components analysis (PCA) of current source density (CSD) waveforms.

We previously reported a novelty P3 reduction in depressed patients compared to healthy controls (n=20 per group) in a novelty oddball task using a 31-channel montage. In an independent replication and extension using a 67-channel montage (n=49 per group), reference-free current source density (CSD) waveforms were simplified and quantified by a temporal, covariance-based principal components an...

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Single Dose Effects of Pascoflair on Current Source Density (CSD) of Human EEG

Pascoflair 425 mg is a herbal drug based on Passiflora incarnata dry extract and is registered in different countries for the treatment of nervous restlessness and anxiety and also as an aid to sleep. The study was initiated for the quantitative assessment of the effect of this preparation on brain electric activity and cognition in human volunteers. Quantitative electroencephalographic current...

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Early effect of NEURAPAS® balance on current source density (CSD) of human EEG

UNLABELLED Psychiatric patients often suffer from stress, anxiety and depression. Various plant extracts are known to fight stress (valerian), anxiety (passion flower) or depression (St. John's wort). NEURAPAS® balance is a mixture of these three extracts and has been designed to cover this complex of psychiatric conditions. The study was initiated to quantitatively assess the effect of this co...

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ژورنال

عنوان ژورنال: Clinical Neurophysiology

سال: 2005

ISSN: 1388-2457

DOI: 10.1016/j.clinph.2005.08.007