RegB/RegA, a Highly Conserved Redox-Responding Global Two-Component Regulatory System

RegB/RegA, a highly conserved redox-responding global two-component regulatory system.

The Reg regulon from Rhodobacter capsulatus and Rhodobacter sphaeroides encodes proteins involved in numerous energy-generating and energy-utilizing processes such as photosynthesis, carbon fixation, nitrogen fixation, hydrogen utilization, aerobic and anaerobic respiration, denitrification, electron transport, and aerotaxis. The redox signal that is detected by the membrane-bound sensor kinase...

Stereochemical Trajectories of a Two-Component Regulatory System PmrA/B in a Colistin-Resistant Acinetobacter baumannii Clinical Isolate

Background: There is limited information on the 3D prediction and modeling of the colistin resistance-associated proteins PmrA/B TCS in Acinetobacter baumannii. We aimed to evaluate the stereochemical structure and domain characterization of PmrA/B in an A. baumannii isolate resistant to high-level colistin, using bioinformatics tools. Methods: The species of the isolate and its susceptibility ...

A Conserved Regulatory System for Aging

that move normally, are fully fertile, and have a normal San Francisco, California 94143 metabolic rate. In addition, it has also been possible to obtain long-lived genetic mosaics that do not produce fat. The fact that these long-lived mutants can appear While many processes in biology, such as cell differenti-so normal makes one optimistic that if this system exists ation and development, inc...

y=Tubulin Is a Highly Conserved Component of the Centrosome

We have cloned and characterized y-tubulin genes from both X. laevis and S. pombe, and partial genes from maize, diatom, and a budding yeast. The proteins encoded by these genes are very similar to each other and to the original Aspergiilus protein, indicating that y-tubuilnsarean ubiquitous and highly conserved subfamily of the tubulln family. A null m’utatlon of the S. pombe gene is lethal. y...

The pleiotropic two-component regulatory system PhoP-PhoQ.