Regulatable gene expression systems for gene therapy applications: progress and future challenges
نویسندگان
چکیده
منابع مشابه
Gene Therapy: Progress and Challenges
Over the past decade, success in the treatment of serious genetic disorders via gene therapy was finally achieved. However, this progress was tempered by the occurrence of serious adverse events related to vector integration into the genome and activation of adjacent proto-oncogenes. Investigators are now focused on retaining the clinical potential of integrating vectors while decreasing the ri...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2005
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2005.03.022