Regulation of IGFBP-2 expression during fasting
نویسندگان
چکیده
منابع مشابه
Regulation of IGFBP-2 expression during fasting
Insulin-like growth factor (IGF)-binding protein-2 (IGFBP-2), one of the most abundant circulating IGFBPs, is known to attenuate the biological action of IGF-1. Although the effect of IGFBP-2 in preventing metabolic disorders is well known, its regulatory mechanism remains unclear. In the present study, we demonstrated the transcriptional regulation of the Igfbp-2 gene by peroxisome-proliferato...
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To investigate the involvement of the insulin-like growth factor (IGF) system in vitamin A (VA)-supported growth, we examined the effects of VA status on IGF binding protein (IGFBP)-2 and -5 gene expression in Japanese quail. VA deficiency caused a reduction in IGFBP-2 mRNA only in lung, without effect in other tissues. However, the expression of IGFBP-5 mRNA was more sensitive to the change of...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2015
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20141248