Regulation of metanephric kidney development by growth/differentiation factor 11
نویسندگان
چکیده
منابع مشابه
Development of the Metanephric Kidney
The metanephric kidney was studied in fetal and older mice beginning at 16 days after mating of the parents. Polyribosomes from fetal kidneys labeled in vitro with 14C-labeled amino acids had 10-20 times more acid-precipitable radioactivity associated with them than polysomes from adult kidneys similarly labeled. Between 3 and 6 days after birth the rate incorporation of labeled amino acids by ...
متن کاملDynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney.
Branching morphogenesis of the metanephric kidney is critically dependent on the delicate orchestration of diverse cellular processes including proliferation, apoptosis, migration, and differentiation. Sphingosine-1-phosphate (S1P) is a potent lipid mediator influencing many of these cellular events. We report increased expression and activity of both sphingosine kinases and S1P phosphatases du...
متن کاملDynamic regulation of sphingosine-1-phosphate homeostasis during development of the mouse metanephric kidney
Branching morphogenesis of the metanephric kidney is critically dependent on the delicate orchestration of diverse cellular processes including proliferation, apoptosis, migration, and differentiation. Sphingosine-1-phosphate (S1P) is a potent lipid mediator influencing many of these cellular events. We report increased expression and activity of both sphingosine kinases and S1P phosphatases du...
متن کاملDEVELOPMENT OF THE METANEPHRIC KIDNEY Protein and Nucleic Acid Synthesis
The metanephric kidney was studied in fetal and older mice beginning at 16 days after mating of the parents. Polyribosomes from fetal kidneys labeled in vitro with 4C-labeled amino acids had 10-20 times more acid-precipitable radioactivity associated with them than polysomes from adult kidneys similarly labeled. Between 3 and 6 days after birth the rate incorporation of labeled amino acids by p...
متن کاملp53 regulates metanephric development.
p53 is best known as a tumor suppressor that regulates cell-cycle, differentiation, and apoptosis pathways, but its potential role in embryonic development and organogenesis remains controversial. Here, p53(-/-) embryos bred on C57Bl6 background exhibited a spectrum of congenital abnormalities of the kidney and urinary tract, including ureteric bud (UB) ectopia, double ureters/collecting system...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2003
ISSN: 0012-1606
DOI: 10.1016/s0012-1606(03)00100-3