Release Behavior of Poly(Lactic Acid-co-Glycolic Acid) Implants Containing Phosphorothioate Oligodeoxynucleotide .
نویسندگان
چکیده
منابع مشابه
Effects of Ultrasound Irradiation on the Release Profile of 5-fluorouracil from Magnetic Polylactic co-glycolic Acid Nanocapsules
Background: Drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. In this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency.Objective: Here, we studies the effects of ultrasound irradiation on the release profile of 5-flu...
متن کاملPractical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid
BACKGROUND Nanoparticles fabricated from the biodegradable and biocompatible polymer, polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug delivery systems. The objective of this study was to explore fully the development of a PLGA nanoparticle drug delivery system for alternative preparation of a commercial formulation. In our nanoparticle fabrication, ou...
متن کاملInvestigation of drug release from paclitaxel loaded polylactic acid nanofibers
Objective(s): In this study, drug loaded electrospun nanofibrous mats were prepared and drug release and mechanism from prepared nanofibers were investigated. Materials and Methods: Paclitaxel (PTX) loaded polylactic acid (PLA) nanofibers were prepared by electrospinning. The effects of process parameters, such as PTX concentration, tip to collector distance, voltage, temperature and flow rate...
متن کاملEvaluation of Ibuprofen Release from Gelatin /Hydroxyapatite /Polylactic Acid Nanocomposites
Gelatin-hydroxyapatite-polylactic acid (PLA) nanocomposites were synthesized using five different formulations. The nanocomposites were loaded with ibuprofen and the amount of drug in the carriers was determined. X-ray diffraction (XRD) analysis was conducted before and after drug loading to ensure the presence of ibuprofen on the nanocomposites. Drug delivery was evaluated in phosphate buffere...
متن کاملEffects of Ultrasound Irradiation on the Release Profile of 5-fluorouracil from Magnetic Polylactic co-glycolic Acid Nanocapsules
BACKGROUND Drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. In this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency. OBJECTIVE Here, we studies the effects of ultrasound irradiation on the release profile of 5-fl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 1997
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.20.455