Replacement of Reactive Phenolic Hydroxyl Groups by Chlorine with Thionyl Chloride and Dimethylformamide
نویسندگان
چکیده
منابع مشابه
Conductivity of Thionyl Chloride-Lithium Tetrachloroaluminate Solutions
The specific conductivity of solutions of LiA1C14 dissolved in SOC12 was determined as a function of composition and temperature. An analytical expression from which the conductivity can be calculated is given as a function of the mole fraction of LiA1C14 and temperature in the ranges from 0 ~ to 0.37~ and from -20 ~ to +70~ respectively. LiAIC14-SOC14 mixtures are used commercially as electrol...
متن کاملRapeseed lecithin hydroxylation by chlorine replacing with hydroxyl groups in chlorinated phospholipids.
Rapeseed lecithin ethanol soluble fraction (LESF) was hydroxylated with 30% hydrogen peroxide in the presence of acetic acid. The product was compared to the one obtained by method based on nucleophilic substitution reaction of phospholipids chlorine derivatives. In this approach, hydrogen chloride was added to double bonds in unsaturated acyl groups of phospholipids. Next, chlorine was replace...
متن کاملChlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride.
Pincer (Phebox)Ir(mesityl)(OAc) (2) (Phebox = 3,5-dimethylphenyl-2,6-bis(oxazolinyl)) complex, formed by benzylic C-H activation of mesitylene (1,3,5-trimethylbenzene) using (Phebox)Ir(OAc)2OH2 (1), was treated with thionyl chloride to rapidly form 1-(chloromethyl)-3,5-dimethylbenzene in 50% yield at 23 °C. A green species was obtained at the end of reaction, which decomposed during flash colum...
متن کاملC1 Nuclear Quadrupole Interaction in Thionyl Chloride
21 hyperfine multiplets, up to J = 12, have been measured for thionyl chloride (S0C12), by means of microwave spectroscopy in the region 18.0 —26.5 GHz. Nuclear quadrupole coupling constants along the principal axes of inertia were determined to be Xaa ~ ~ 25.004 ± 0.040 MHz, Xbb = 0.009 ± 0.025 MHz and Xce = 25.013 ± 0.031 MHz. Also, coupling constants along the S—CI bond axis (z axis) and two...
متن کاملChiral ruthenium(II) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα.
A series of novel chiral ruthenium(II) complexes with phenolic hydroxyl groups were synthesized and characterized. These ruthenium(II) complexes exhibited strong dual inhibition of topoisomerases I and IIα, with approximate IC50 values of 3-15 mM, which were more efficient than the widely clinically used single TopoI poison camptothecin (CPT) or TopoIIα poison etoposide (VP-16). Δ-1 and Λ-1 wit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1965
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.85.6_544